|SQAB Tutorial: Back to the Lab: Human Behavioral Pharmacology Methods, Outcomes and Meanings
|Saturday, May 23, 2020
|12:00 PM–12:50 PM
|Marriott Marquis, Level M2, Marquis Ballroom 6
|Area: SCI; Domain: Basic Research
|BACB/PSY/QABA CE Offered. CE Instructor: William Stoops, Ph.D.
|Chair: Derek D. Reed (University of Kansas)
|Presenting Author: WILLIAM STOOPS (University of Kentucky)
Human behavioral pharmacology methods have been used to rigorously evaluate the effects of a range of centrally acting drugs in human beings under controlled conditions. Methods like drug self-administration and drug-discrimination have been adapted from non-human laboratory animal models. Because humans have the capacity to communicate verbally, self-report methods are also commonly used to understand drug effects. This presentation will provide an overview of these traditional human behavioral pharmacology methods, as well as more novel measures that have been introduced to the field. Representative data will be shared and the benefits, challenges and translational relevance of each method will be discussed. This session will cover guiding principles in the design of human behavioral pharmacology studies (e.g., using placebo controls, testing multiple doses) along with ethical (e.g., avoiding enrollment of individuals seeking treatment, determining capacity to consent) and safety (e.g., dose selection, pre-screening of participants for exclusionary health problems) that must be addressed when conducting these types of studies.
|Instruction Level: Intermediate
Board certified behavior analysts; licensed psychologists; graduate students.
|Learning Objectives: At the conclusion of the presentation, participants will be able to: (1) understand basic methods used in human behavioral pharmacology research; (2) know how ethical and safety issues are addressed in human behavioral pharmacology studies; (3) appreciate the clinical relevance of human behavioral pharmacology findings.
|WILLIAM STOOPS (University of Kentucky)
|Dr. William W. Stoops, a Professor in the Departments of Behavioral Science, Psychiatry and Psychology at the University of Kentucky, earned his Bachelor’s degree in Psychology from Davidson College in Davidson, NC and his Master’s degree and Ph.D. in Psychology from the University of Kentucky. His research evaluates the behavioral and pharmacological factors that contribute to drug use disorders, focusing primarily on stimulant drugs. Dr. Stoops’ research contributions resulted in receipt of the 2016 Psychologist of the Year Award from the Kentucky Psychological Association, the 2013 Joseph Cochin Young Investigator Award from the College on Problems of Drug Dependence and the 2008 Wyeth Young Psychopharmacologist Award from Division 28 (Psychopharmacology and Substance Abuse) of the American Psychological Association (APA). Dr. Stoops currently serves on the College on Problems of Drug Dependence Board of Directors and is Editor of Experimental and Clinical Psychopharmacology.