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| Targeted Medication Treatments for Behavioral Features of Autism and Fragile X – Research Trial Results and Challenges |
| Saturday, May 27, 2023 |
| 3:00 PM–3:50 PM |
| Convention Center Four Seasons Ballroom 1 |
| Area: DDA; Domain: Applied Research |
| Chair: Patrick Romani (University of Colorado, Anschutz Medical Campus) |
| CE Instructor: Nicole Tartaglia, M.D. |
| Presenting Author: NICOLE TARTAGLIA (University of Colorado School of Medicine and Children's Hospital Colorado) |
| Abstract: Advances in neuroscience have led to discovery of many potential medication targets for treatment of behavioral and cognitive disorders in autism spectrum disorder and other neurogenetic syndromes, leading to many different clinical research trials in these conditions. This presentation will introduce audiences to the different pharmaceutical trials targeting behavioral outcomes, including trials of glutamate antagonists and GABA agonists in Fragile X syndrome, and vasopressin antagonists and cannabidiol (CBD) for treatment of irritability and anxiety in autism. We will also discuss some of the challenges in designing and executing medication trials targeting behavioral outcomes in individuals with autism and other developmental disabilities, and the unmet need for strong behavioral outcome measures for use in pharmaceutical trials. |
| Instruction Level: Intermediate |
| Target Audience: The target audience includes those interested in medication treatment trials and research in autism and developmental disabilities, those involved in the development of new tools and strategies to measure behavioral outcomes in clinical trials |
| Learning Objectives: At the conclusion of the presentation, participants will be able to: (1) Understand the results of recent medication trials targeting behavior in autism, Fragile X and other neurogenetic conditions; (2) List challenges faced by investigators studying new medication treatments for behavioral and neurodevelopmental disorders; (3) Recognize important components of the tools needed to study behavioral outcomes in pharmaceutical trials |
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| NICOLE TARTAGLIA (University of Colorado School of Medicine and Children's Hospital Colorado) |
 Nicole Tartaglia, MD, MS is a Developmental-Behavioral Pediatrician and Professor of Pediatrics at University of Colorado School of Medicine and Children's Hospital Colorado. She completed her medical education and graduate studies in Clinical Investigation at University of Colorado, Pediatric training at Children's Hospital Los Angeles, and fellowship training in Developmental-Behavioral Pediatrics at the University of California Davis MIND Institute. Since 2007, she has been Director of the Denver Fragile X Clinic for children and adults affected by mutations in the FMR1 gene and Director of the eXtraordinarY Kids Clinic for individuals with sex chromosome disorders serving patients from the prenatal period to adulthood. She leads a research team focused on identifying behavioral phenotypes in these neurogenetic disorders, and conducting clinical trials for investigational medications targeting behavioral and developmental outcomes in Fragile X, autism, and sex chromosome disorders. Her clinical practice focuses on neurodevelopmental care and psychopharmacologic medication management for psychological and behavioral challenges in children and adolescents with autism, ADHD, intellectual disability and neurogenetic disorders. She lives in Colorado with her husband and 2 children, and enjoys hiking, snowboarding, backpacking, red wine, and social engagements with friends, colleagues, and family. |
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 Advancing Racial Equity in Applied Behavior Analysis: Autism as a Case Example |
| Saturday, May 27, 2023 |
| 4:00 PM–4:50 PM |
| Convention Center Four Seasons Ballroom 1 |
| Area: DEI; Domain: Service Delivery |
| Chair: Jomella Watson-Thompson (University of Kansas) |
| CE Instructor: Brian Boyd, Ph.D. |
| Presenting Author: BRIAN BOYD (University of North Carolina) |
| Abstract: In many ways, autism research is at a crossroads. There are debates over the language used to describe the condition, the interventions provided to those who are autistic, and who should have a voice in articulating any future research agenda. In these debates, we sometimes fail to acknowledge that autistic people and their families are not a monolithic group and can occupy multiple minoritizing identities. These multiple minoritizing identifies, such as being black and autistic, can affect their access to quality services, life experiences, and outcomes. Thus, there have been increasing calls to better center equity within autism research and practice to address long-standing disparities that exist along socioeconomic and racial lines. This presentation will (a) highlight research that demonstrates existing disparities; (b) discuss strategies for advancing racial equity within clinical practice, including within ABA-based interventions; and (c) describe a path forward for autism research and practice. |
| Instruction Level: Intermediate |
| Target Audience: Researchers and Clinicians |
| Learning Objectives: At the conclusion of the presentation, participants will be able to: (1) Describe the state of autism research showcasing existing disparities; (2) Describe strategies to promote more culturally focused care; (3) Discuss ways to better center equity within autism research and practice |
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| BRIAN BOYD (University of North Carolina) |
 Brian A. Boyd is the William C. Friday Distinguished Professor in Education in the School of Education at the University of North Carolina at Chapel Hill. He was previously the Director of the Juniper Gardens Children’s Project at the University of Kansas. Dr. Boyd is quite engaged in research that involves the most vulnerable, and often marginalized, populations. As a special educator by training, much of his research has involved the development and evaluation of evidence-based practices that could be implemented within school and home contexts. His more recent work has focused on how issues of implicit bias and race affect the outcomes of children with and without disabilities. Dr. Boyd’s research has been continuously funded by federal agencies such as the Institute of Education Sciences and National Institutes of Health. Currently, he serves as Vice President of the International Society for Autism Research and Co-Editor of the Journal of Early Intervention. He also serves on multiple national boards that are dedicated to improving the outcomes of autistic persons and those from historically underserved communities. |
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| Equity in Education: How to Leverage Existing Systems and Resources to Support Positive Student Outcomes |
| Saturday, May 27, 2023 |
| 4:00 PM–4:50 PM |
| Convention Center 401/402 |
| Area: EDC; Domain: Service Delivery |
| Chair: Tai Collins (University of Cincinnati) |
| CE Instructor: Tamika La Salle, Ph.D. |
| Presenting Author: TAMIKA LA SALLE-FINLEY (Georgia State University) |
| Abstract: This keynote will focus on breaking the silos that inadvertently separate related and overlapping school efforts to promote positive student outcomes for students with minoritized and marginalized identities. Attendees will learn how to leverage related data to inform cultural responsive and affirming practices with students from marginalized and minoritized backgrounds. Recommendations for practice will be discussed. |
| Instruction Level: Intermediate |
| Target Audience: ABA Practitioners, professionals working in schools |
| Learning Objectives: At the conclusion of the presentation, participants will be able to: (1) Describe the impact of school climate on student outcomes- particularly for students with marginalized and minoritized identities; (2) Discuss how to leverage MTSS systems to meet needs at the universal and targeted levels based on relevant and integrated data; (3) Discuss key components of equity, cultural responsiveness and social justice as they relate to school climate |
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| TAMIKA LA SALLE-FINLEY (Georgia State University) |
 Dr. Tamika La Salle is an Associate Professor of School Psychology at Georgia State University and the Director of the Center for Research on School Safety, School Climate. She is also the editor-in -Chief of the International Journal of School & Educational Psychology. Dr. La Salle’s research focuses on the impact of school climate on the outcomes of students, particularly those with minoritized and marginalized identities. Dr. La Salle also serves as an educational consultant; She Is particularly interested in the impact of culture on students’ educational experiences and on developing and maintaining culturally responsive school environments that are equitable, safe, and positive for students, teachers, and families. |
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