Abstract: Clinical settings, as with any organization, face their own set of unique challenges and opportunities. Whether youï¿½re a new clinician or a veteran leader there are going to be some habits youï¿½re trying to get rid of and new habits youï¿½re trying to build. Building safe, ethical, and practical habits in your particular clinical setting can lead to demonstrable value, and ensuring your management systems are sustainable and replicable can change your culture and impact growth. The purpose of this address is to discuss safety in the context of organizational culture and multi-level management solutions, while offering tips for sustainable clinical safety systems. Learning Objectives: At the conclusion of the presentation, participants will be able to: (1) define safety priorities using an objective and positive approach; (2) explain the role leadership has on sustainable safety solutions; (3) list ways to help ensure safety initiatives are effective and performance improvements last.