Challenging behavior continues to plague both primary and secondary schools, despite a raft of educational and governmental policies to tackle it. The need for practical, relevant, and evidence-based strategies for analyzing and treating these behaviors has never been more pressing than it is today. Behavior analysis certainly has much to offer with regard to helping schools solve problems and achieve the goals set for both students and teachers. However, our literature has tended to focus less on applications of our science to typically developing children and adolescents, so there is still much we don't know about the nuances of working with these populations. This presentation will address some of the challenges associated with applying functional analysis and intervention strategies in mainstream classrooms, as well as delineating some possible solutions derived from both research and clinical practice. Further, it will suggest some research questions that may be important if behavior analysis is to fulfill its promise to mainstream students, their parents, and their teachers.